Wales captain Sam Warburton will return to the starting XV in the first Test of the three-match series against New Zealand at Eden Park on Saturday.
Cardiff Blues back-rower Warburton sustained a shoulder injury in April and missed the 27-13 defeat to England at Twickenham on May 29.
Warburton returns to the line-up in place of Dan Lydiate, who was left out of the touring party as he prepares to undergo surgery on his shoulder.
Alun Wyn Jones is set to make his 100th Wales appearance, while the other changes see Gethin Jenkins, Ken Owens, Bradley Davies and Jonathan Davies restored.
Uncapped flanker Ellis Jenkins has been named as a replacement and head coach Warren Gatland believes the tour provides chances to a number of individuals looking to stake a claim for a regular spot.
He said: "We have made five changes since our last hit out and there is an opportunity for a number of players.
"It's an opportunity for a couple of boys to start and we are bringing in experience with Gethin, Ken and Bradley.
"In the midfield it's nice to have that experienced combination back and the players who move to the bench will still have an impact on game day.
"We are under no illusions how tough the test series will be against the back-to-back world champions but the players are also aware how important this tour is."
Wales: Liam Williams, George North, Jonathan Davies, Jamie Roberts, Hallam Amos, Dan Biggar, Rhys Webb; Gethin Jenkins, Ken Owens, Samson Lee, Bradley Davies, Alun Wyn Jones, Ross Moriarty, Sam Warburton, Taulupe Faletau.
Replacements: Scott Baldwin, Rob Evans, Tomas Francis, Jake Ball, Ellis Jenkins, Gareth Davies, Gareth Anscombe, Scott Williams.