Fly-half Nicolas Sanchez led Argentina to a 30-19 win over an experimental France side on Sunday.
Sanchez finished with 15 points off his boot as the Pumas, who led 17-3 after half an hour but had to battle back late, secured their victory.
France coach Guy Noves was without numerous players due to the Top 14 semi-finals, leading to seven uncapped players being named in the team.
Tries from Manuel Montero and Joaquin Tuculet, and the boot of Sanchez, put Argentina in early control before Remi Bonfils crossed for France late in the first half.
Jules Plisson converted two penalties shortly after the break to put the visitors ahead before Sanchez responded and a Guido Petti Pagadizabal try secured the Pumas' win.
Javier Ortega Desio and Jefferson Poirot were shown yellow cards in the second half.
The teams will meet again on Saturday.