Harlequins director of rugby Conor O'Shea will leave the club at the end of the season.
O'Shea, who assumed the post in 2010, has enjoyed great success in his time at The Stoop, with Harlequins winning the Amlin Challenge Cup, Premiership and LV Cup during his stint.
The 45-year-old former Ireland international revealed last month he had rejected an approach from Italy to become their head coach.
But he is now poised to end his association with Harlequins, who will be making no further announcement until a replacement is appointed.
O'Shea told Harlequins' official website: "I will have been very fortunate to have had the opportunity to contribute to this special club for over six years come May.
"I have enjoyed working with everybody at Harlequins, from the players to the staff to the supporters, having said that, the end of this season is the right time for me to move on.
"We have a very talented group of players and coaches who are intent on securing silverware this season and that is my sole focus and where all our efforts are concentrated.
"I will say my goodbyes when the season is over."